Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Sucrose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.59 |
| ▸ | SELL | P14151 | 3/20 | 0.44 |
| ▸ | SELP | P16109 | 3/20 | 0.44 |
| ▸ | SELE | P16581 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GJB2 | P29033 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sucrose SCHEMBL949885 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL285512 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL1067854 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL5030245 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL1874820 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL21121139 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL3944704 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL16859920 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL285432 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE | |
| Sucrose SCHEMBL3947585 | 1.00 | CDK1 (0.59) | CDK1CCNB1SELLSELPSELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4770634-A | DENTISTRY | LACLEDE, INC. | 1988-09-13 | — | — | US | claimed |