Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 11/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 11/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696220 | 0.99 | SIRT2 (0.41) | LTB4RLTB4R2SIRT2PPARGPPARD | |
| SCHEMBL10694981 | 0.92 | LTB4R (0.42) | LTB4RLTB4R2SIRT2PPARGPPARD | |
| SCHEMBL10344474 | 0.91 | SIRT2 (0.41) | LTB4RLTB4R2SIRT2PPARGPPARD | |
| SCHEMBL10344115 | 0.85 | PPARG (0.56) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10344377 | 0.84 | PPARG (0.57) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10344393 | 0.84 | LTB4R (0.42) | LTB4RLTB4R2SIRT2PPARGPPARD | |
| SCHEMBL10707461 | 0.83 | LTB4R (0.41) | LTB4RLTB4R2SIRT2PPARGPPARD | |
| SCHEMBL10689515 | 0.78 | LTB4R (0.41) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10344546 | 0.78 | LTB4R (0.41) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10344328 | 0.76 | LTB4R (0.40) | LTB4RLTB4R2PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261254-A1 | 3,4-Dihydro-4-oxo-2H-1-benzopyranyloxy alkanoic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-03-30 | — | — | EP | disclosed |
| US-4650812-A | ANTIALLERGY | HOFFMANN-LA ROCHE INC. (US) | 1987-03-17 | — | — | US | disclosed |