Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 18/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694092 | 1.00 | MME (0.52) | MMEALDH1A1GAATSHR | |
| SCHEMBL9470310 | 0.94 | MME (0.45) | MMEALDH1A1GAATSHR | |
| SCHEMBL9470317 | 0.94 | MME (0.45) | MMEALDH1A1GAATSHR | |
| SCHEMBL9470067 | 0.82 | MME (0.53) | MMEALDH1A1GAA | |
| SCHEMBL9470070 | 0.82 | MME (0.53) | MMEALDH1A1GAA | |
| SCHEMBL9469460 | 0.82 | MME (0.64) | MME | |
| SCHEMBL9469463 | 0.82 | MME (0.64) | MME | |
| SCHEMBL9469610 | 0.80 | MME (0.60) | MMEALDH1A1GAATSHR | |
| SCHEMBL9469613 | 0.80 | MME (0.60) | MMEALDH1A1GAATSHR | |
| SCHEMBL10687230 | 0.79 | MME (0.50) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274234-A2 | Spiro-subsituted glutaramide diuretic agents | Pfizer Limited (GB) | 1988-07-13 | — | — | EP | disclosed |