Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469460 | 1.00 | MME (0.64) | MMESMN1; SMN2 | |
| SCHEMBL9470545 | 0.87 | MME (0.83) | MME | |
| SCHEMBL9470536 | 0.87 | MME (0.83) | MME | |
| SCHEMBL10694097 | 0.82 | MME (0.52) | MME | |
| SCHEMBL10694092 | 0.82 | MME (0.52) | MME | |
| SCHEMBL7452607 | 0.77 | MME (0.78) | MME | |
| SCHEMBL7444175 | 0.77 | MME (0.78) | MME | |
| SCHEMBL7446878 | 0.76 | MME (1.00) | MME | |
| SCHEMBL7445415 | 0.76 | MME (1.00) | MME | |
| SCHEMBL9470317 | 0.76 | MME (0.45) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192800-A | Hypotensive agents | PFIZER INC. (US) | 1993-03-09 | — | — | US | disclosed |
| US-5030654-A | Glutaramide diuretic agents | PFIZER INC. (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0274234-A2 | Spiro-subsituted glutaramide diuretic agents | Pfizer Limited (GB) | 1988-07-13 | — | — | EP | disclosed |