Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5932634 | 0.83 | HPGD (0.68) | KMT2AHPGDSMN1; SMN2MEN1CYP3A4 | |
| Bromide SCHEMBL10777716 | 0.81 | HPGD (0.65) | KMT2AHPGDSMN1; SMN2MEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9432569 | 0.81 | HPGD (0.65) | KMT2AHPGDSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL6046322 | 0.80 | KMT2A (0.58) | KMT2AHPGDSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL6505373 | 0.80 | HPGD (0.58) | KMT2AHPGDSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL18503706 | 0.79 | HPGD (0.62) | KMT2AHPGDSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL18306239 | 0.79 | HPGD (0.62) | KMT2AHPGDSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL10693554 | 0.79 | MEN1 (0.47) | KMT2AHPGDSMN1; SMN2MEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11607572 | 0.78 | KMT2A (0.56) | KMT2AHPGDSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL12781699 | 0.78 | HPGD (0.60) | KMT2AHPGDSMN1; SMN2MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |