Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22221979 | 0.84 | MAPT (0.56) | MEN1CYP3A4HPGDKMT2AMAPK1 | |
| SCHEMBL11913604 | 0.82 | MAPT (0.54) | MEN1CYP3A4HPGDKMT2AMAPK1 | |
| SCHEMBL18306239 | 0.82 | HPGD (0.62) | MEN1CYP3A4HPGDKMT2AMAPK1 | |
| SCHEMBL13365304 | 0.80 | HPGD (0.60) | MEN1CYP3A4HPGDKMT2AMAPK1 | |
| SCHEMBL16476536 | 0.79 | MEN1 (0.50) | MEN1CYP3A4HPGDKMT2AMAPK1 | |
| SCHEMBL17268901 | 0.79 | HDAC1 (0.59) | MEN1CYP3A4HPGDKMT2AMAPK1 | |
| SCHEMBL11310671 | 0.79 | GAA (0.53) | MEN1CYP3A4HPGDKMT2AMAPK1 | |
| SCHEMBL10694146 | 0.79 | KMT2A (0.54) | MEN1CYP3A4HPGDKMT2AMAPK1 | |
| SCHEMBL19477872 | 0.79 | MEN1 (0.54) | MEN1CYP3A4HPGDKMT2AMAPK1 | |
| SCHEMBL16248729 | 0.78 | L3MBTL1 (0.48) | MEN1CYP3A4HPGDKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254318-A2 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-27 | — | — | EP | disclosed |
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |