Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400798 | 0.83 | ALDH1A1 (0.47) | NPSR1CTSLCTSBCTSKCARM1 | |
| SCHEMBL3099776 | 0.79 | MEN1 (0.44) | NPSR1CTSLCTSBCTSKCARM1 | |
| SCHEMBL27604695 | 0.74 | DPP7 (0.48) | NPSR1CTSLCTSBCTSKHTT | |
| SCHEMBL2401169 | 0.74 | CARM1 (0.52) | NPSR1CTSLCTSBCTSKCARM1 | |
| SCHEMBL2402365 | 0.72 | NPSR1 (0.46) | NPSR1CTSLCTSBCTSKCARM1 | |
| SCHEMBL3314944 | 0.70 | ALDH1A1 (0.57) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL3314942 | 0.70 | ALDH1A1 (0.57) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL3105144 | 0.70 | HRH3 (0.47) | NPSR1CTSLCTSBCTSKCARM1 | |
| SCHEMBL2399783 | 0.69 | NPSR1 (0.49) | NPSR1CTSLCTSBCTSKCARM1 | |
| SCHEMBL2401685 | 0.69 | MEN1 (0.48) | NPSR1CTSLCTSBCTSKCARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |