SCHEMBL10694318

SCHEMBL10694318

O=C1c2ccccc2C(=O)N1CCOc1c2ccccc2cc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.54
NPSR1 Q6W5P4 1/20 0.54
RAB9A P51151 7/20 0.52
TSHR P16473 3/20 0.52
NPC1 O15118 2/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.51
MAPK1 P28482 1/20 0.51
ALDH1A1 P00352 1/20 0.49
MAPT P10636 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10694879 0.93 RAB9A (0.59) HPGDNPSR1RAB9ATSHRNPC1
SCHEMBL10694245 0.91 RAB9A (0.54) HPGDNPSR1RAB9ATDP1L3MBTL1
SCHEMBL10696014 0.90 MAPT (0.52) HPGDNPSR1RAB9ATDP1L3MBTL1
SCHEMBL10688314 0.90 MAPT (0.52) HPGDNPSR1RAB9ATDP1L3MBTL1
SCHEMBL10691871 0.90 MAPT (0.52) HPGDNPSR1RAB9ATDP1L3MBTL1
SCHEMBL10692567 0.90 MAPT (0.52) HPGDNPSR1RAB9ATDP1L3MBTL1
SCHEMBL10692842 0.90 MAPT (0.52) HPGDNPSR1RAB9ATDP1L3MBTL1
SCHEMBL10695466 0.90 MAPT (0.52) HPGDNPSR1RAB9ATDP1L3MBTL1
SCHEMBL10695966 0.90 MAPT (0.52) HPGDNPSR1RAB9ATDP1L3MBTL1
SCHEMBL10694016 0.90 MAPT (0.52) HPGDNPSR1RAB9ATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4792551-A 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents SYNTEX (U.S.A.) INC. (US) 1988-12-20 US disclosed
EP-0132351-A2 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them SYNTEX (U.S.A.) INC. (US) 1985-01-30 EP disclosed