Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MVD | P53602 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | SAT1 | P21673 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809290 | 0.92 | CYP3A4 (0.44) | PPARDCYP3A4BTN3A1LPAR3LPAR1 | |
| Ammonia Solution, Strong SCHEMBL28481503 | 0.90 | CYP3A4 (0.43) | PPARDCYP3A4BTN3A1LPAR3LPAR1 | |
| SCHEMBL8837386 | 0.90 | BTN3A1 (0.39) | PPARDCYP3A4PLA2G2CBTN3A1MVD | |
| SCHEMBL146205 | 0.90 | TSHR (0.46) | PPARDCYP3A4PLA2G2CBTN3A1LPAR3 | |
| SCHEMBL141690 | 0.87 | CYP3A4 (0.44) | PPARDCYP3A4BTN3A1LPAR3LPAR1 | |
| SCHEMBL10425531 | 0.85 | CYP3A4 (0.39) | PPARDCYP3A4BTN3A1LPAR3LPAR1 | |
| SCHEMBL14299009 | 0.84 | TSHR (0.42) | PPARDCYP3A4BTN3A1LPAR3LPAR1 | |
| SCHEMBL28739951 | 0.83 | CYP3A4 (0.54) | PPARDCYP3A4PLA2G2CLPAR3LPAR1 | |
| SCHEMBL309468 | 0.81 | BTN3A1 (0.47) | PPARDCYP3A4BTN3A1LPAR3LPAR1 | |
| SCHEMBL9719935 | 0.81 | ALDH1A1 (0.52) | PPARDBTN3A1MVD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270033-A2 | Polyesterpolyols and use thereof in the production of polyurethane foams | ECP ENICHEM POLIMERI S.r.l. (IT) | 1988-06-08 | — | — | EP | disclosed |