Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513938 | 0.74 | POLB (0.32) | LMNATSHRNPSR1KDM4E | |
| SCHEMBL9717712 | 0.62 | POLB (0.32) | LMNATSHRKDM4E | |
| SCHEMBL13209004 | 0.60 | LMNA (0.48) | LMNATSHRNPSR1KDM4ECYP2C19 | |
| SCHEMBL542612 | 0.60 | LMNA (0.48) | LMNATSHRNPSR1KDM4ECYP2C19 | |
| SCHEMBL13209012 | 0.60 | LMNA (0.48) | LMNATSHRNPSR1KDM4ECYP2C19 | |
| SCHEMBL11580974 | 0.59 | LMNA (0.46) | LMNATSHRNPSR1KDM4E | |
| SCHEMBL14236463 | 0.58 | LMNA (0.35) | LMNAKDM4EPDE7A | |
| SCHEMBL8348835 | 0.58 | LMNA (0.59) | LMNATSHRNPSR1KDM4ECYP2C19 | |
| SCHEMBL16253384 | 0.58 | SMN1; SMN2 (0.31) | TSHR | |
| SCHEMBL9579188 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4767542-A | CHLORO-AND BROMO DERIVATIVES | PPG INDUSTRIES, INC. (US) | 1988-08-30 | — | — | US | disclosed |