Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.60 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ICMT | O60725 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | KLK7 | P49862 | 2/20 | 0.56 |
| ▸ | PAM | P19021 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21838310 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1MEN1NPC1POLB | |
| SCHEMBL11114167 | 0.90 | SOAT2 (0.71) | SMN1; SMN2ALDH1A1MEN1NPC1POLB | |
| SCHEMBL16409794 | 0.84 | EPHX2 (0.66) | SOAT2SOAT1GAAHPGDICMT | |
| SCHEMBL9388173 | 0.83 | SOAT2 (0.82) | ALDH1A1POLBSOAT2SOAT1ICMT | |
| SCHEMBL8743258 | 0.83 | SOAT2 (0.82) | ALDH1A1POLBSOAT2SOAT1ICMT | |
| SCHEMBL8743085 | 0.83 | SOAT2 (0.82) | ALDH1A1POLBSOAT2SOAT1ICMT | |
| SCHEMBL282938 | 0.83 | SOAT2 (0.82) | ALDH1A1POLBSOAT2SOAT1ICMT | |
| SCHEMBL541399 | 0.83 | SOAT2 (0.82) | ALDH1A1POLBSOAT2SOAT1ICMT | |
| SCHEMBL8742971 | 0.83 | SOAT2 (0.82) | ALDH1A1POLBSOAT2SOAT1ICMT | |
| SCHEMBL8743011 | 0.83 | SOAT2 (0.82) | ALDH1A1POLBSOAT2SOAT1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |