Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28665630 | 0.79 | EPHX2 (1.00) | EPHX2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22411430 | 0.76 | EPHX2 (0.95) | EPHX2KDM4ERAB9AMAPTHDAC3 | |
| SCHEMBL29510584 | 0.75 | MAPT (0.78) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL20553719 | 0.75 | MAPT (0.78) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL10693670 | 0.75 | EPHX2 (0.56) | EPHX2CNR1FAAHCNR2 | |
| SCHEMBL10695972 | 0.75 | EPHX2 (0.56) | EPHX2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10180474 | 0.75 | EPHX2 (0.93) | EPHX2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10180472 | 0.75 | EPHX2 (0.93) | EPHX2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20553952 | 0.75 | MAPT (0.79) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL30038291 | 0.75 | MAPT (0.79) | MEN1KMT2AALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |