Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593150 | 0.89 | GPBAR1 (0.56) | CYSLTR1GPBAR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL10696449 | 0.87 | CYSLTR1 (0.48) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL9636913 | 0.83 | CYSLTR1 (0.58) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7710953 | 0.83 | CYSLTR1 (0.53) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7452392 | 0.80 | CYSLTR1 (0.54) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6089876 | 0.79 | GPBAR1 (0.68) | CYSLTR1GPBAR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL7808139 | 0.79 | CYSLTR1 (0.56) | CYSLTR1GPBAR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL7921075 | 0.79 | GPBAR1 (0.53) | CYSLTR1GPBAR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL6090813 | 0.79 | CYSLTR1 (0.69) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL9847314 | 0.78 | CYSLTR1 (0.58) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769461-A | Quinolinyl benzene hydroxamic acids as anti-inflammatory/antiallergic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-09-06 | — | — | US | disclosed |