Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593150 | 0.89 | GPBAR1 (0.56) | GPBAR1CYSLTR1CYSLTR2ALOX5FFAR1 | |
| SCHEMBL9081199 | 0.83 | CYSLTR1 (0.61) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL9847314 | 0.83 | CYSLTR1 (0.58) | GPBAR1CYSLTR1CYSLTR2PLA2G1B | |
| SCHEMBL28030524 | 0.82 | NPC1 (0.57) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL9018928 | 0.81 | GPBAR1 (0.46) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL7504604 | 0.80 | CYSLTR1 (0.58) | GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL8902567 | 0.80 | ALOX5 (0.72) | GPBAR1CYSLTR1CYSLTR2ALOX5FFAR1 | |
| SCHEMBL29877127 | 0.79 | CYP1A2 (0.63) | GPBAR1CYSLTR1CYSLTR2ALOX5AKR1B1 | |
| SCHEMBL5503169 | 0.79 | CYP1A2 (0.63) | GPBAR1CYSLTR1CYSLTR2ALOX5AKR1B1 | |
| SCHEMBL8834234 | 0.79 | GPBAR1 (0.57) | GPBAR1CYSLTR1CYSLTR2ALOX5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530639-B1 | Quinolylmethoxy-phenylacetamides substituted by a heterocycle as lipoxygenase inhibitors | BAYER AG (DE) | 1994-08-17 | — | — | EP | claimed |
| US-5310744-A | Antiinflammatory | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | claimed |
| US-5266578-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | claimed |
| US-6277833-B1 | 3-HYDROXY-3-METHYL-GLUTARYL COENZYME A (HGM--COA) REDUCTASE INHIBITORS WHICH RETARD CHOLESTEROL BIOSYNTHESIS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-21 | — | — | US | disclosed |
| US-5861385-A | Substituted triols | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | disclosed |
| US-5310744-A | Antiinflammatory | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5310744-A | Antiinflammatory | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5310744-A | Antiinflammatory | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5266578-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| EP-0545170-A1 | Quinolylmethoxyphenylacetamides | BAYER AG (DE) | 1993-06-09 | — | — | EP | disclosed |
| EP-0530639-A1 | Quinolylmethoxy-phenylacetamides substituted by a heterocycle as lipoxygenase inhibitors | BAYER AG (DE) | 1993-03-10 | — | — | EP | disclosed |