SCHEMBL10694559

SCHEMBL10694559

Nc1cc(Cl)c(S(=O)(=O)Nc2ccc(S(=O)(=O)O)cc2)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.51
NPSR1 Q6W5P4 1/20 0.51
PGR P06401 1/20 0.47
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPK1 P28482 1/20 0.44
CES1 P23141 1/20 0.42
ALDH1A1 P00352 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
POLB P06746 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PRMT1 Q99873 1/20 0.41
ITGA1 P56199 1/20 0.41
HTT P42858 1/20 0.41
LMNA P02545 1/20 0.41
PKM P14618 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL11685427 0.99 MAPT (0.50) MAPTNPSR1PGRMEN1KMT2A
SCHEMBL10594395 0.88 PGR (0.58) MAPTPGRMEN1KMT2AMAPK1
SCHEMBL11848559 0.87 PGR (0.57) MAPTPGRMEN1KMT2AMAPK1
SCHEMBL10726228 0.87 PGR (0.57) MAPTPGRMEN1KMT2AMAPK1
SCHEMBL10691537 0.85 MEN1 (0.53) PGRMEN1KMT2AALDH1A1SMN1; SMN2
Methane SCHEMBL11684145 0.84 MEN1 (0.52) PGRMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL11682324 0.83 MCL1 (0.48) MEN1KMT2AALDH1A1HSD17B10CA1
SCHEMBL11685839 0.83 MCL1 (0.49) MAPTNPSR1MEN1KMT2AALDH1A1
SCHEMBL11685280 0.83 KMT2A (0.50) MAPTNPSR1MEN1KMT2AALDH1A1
SCHEMBL10692669 0.82 MAPT (0.57) MAPTNPSR1PGRKMT2ACES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
EP-0112285-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-03-18 EP disclosed
EP-0112285-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed
US-4180503-A FOR DYEING POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-12-25 US disclosed
US-4124581-A FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST BAYER AKTIENGESELLSCHAFT (DE) 1978-11-07 US disclosed
US-4060521-A POLYAMIDE BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 US disclosed