Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 9/20 | 0.59 |
| ▸ | DRD3 | P35462 | 10/20 | 0.56 |
| ▸ | DRD4 | P21917 | 6/20 | 0.54 |
| ▸ | DRD1 | P21728 | 4/20 | 0.54 |
| ▸ | DRD5 | P21918 | 4/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | PRCP | P42785 | 1/20 | 0.53 |
| ▸ | EBP | Q15125 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352771 | 0.84 | ACHE (0.71) | ACHEDRD2DRD3DRD4DRD1 | |
| SCHEMBL10352770 | 0.84 | ACHE (0.71) | ACHEDRD2DRD3DRD4DRD1 | |
| SCHEMBL10415369 | 0.82 | ACHE (0.74) | ACHEDRD2DRD3DRD4DRD1 | |
| Hydrochloric Acid SCHEMBL7312403 | 0.82 | ACHE (0.67) | ACHEDRD2DRD3DRD4DRD1 | |
| SCHEMBL10352749 | 0.81 | ACHE (0.78) | ACHEDRD2DRD3DRD4DRD1 | |
| SCHEMBL10352748 | 0.81 | ACHE (0.78) | ACHEDRD2DRD3DRD4DRD1 | |
| Hydrochloric Acid SCHEMBL7319382 | 0.80 | ACHE (0.77) | ACHEDRD2DRD3DRD4DRD1 | |
| Hydrochloric Acid SCHEMBL7312417 | 0.79 | ACHE (0.68) | ACHEDRD2DRD3DRD4DRD1 | |
| SCHEMBL10352966 | 0.78 | ACHE (0.71) | ACHEDRD2DRD3DRD4DRD1 | |
| SCHEMBL10352965 | 0.78 | ACHE (0.71) | ACHEDRD2DRD3DRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719219-A | Phenyl-azacycloalkanes and use thereof in treatment of central nervous system disorders | Carlsson, Per A. E. (SE) | 1988-01-12 | — | — | US | claimed |
| EP-0143757-A2 | Novel substituted phenylazacycloalkanes, process for preparation and pharmaceutical preparations for such compounds | Carlsson, Per Arvid Emil (SE) | 1985-06-05 | — | — | EP | claimed |