Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690104 | 0.97 | MEN1 (0.55) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL10693562 | 0.90 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9APAX8 | |
| SCHEMBL10695458 | 0.82 | PTGIR (0.52) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL9676729 | 0.81 | ALDH1A1 (0.59) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL10694993 | 0.81 | CHRM5 (0.54) | MEN1KMT2ANPC1RAB9AALOX5 | |
| SCHEMBL4456605 | 0.77 | SMN1; SMN2 (0.52) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL11794701 | 0.77 | ALDH1A1 (0.45) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL10694263 | 0.77 | CNR2 (0.54) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL10991682 | 0.77 | MEN1 (0.60) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL10690647 | 0.75 | CHRM5 (0.56) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |