Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533630 | 0.78 | KDM4E (0.62) | ALDH1A1KDM4EHPGDHSD17B10PARP1 | |
| SCHEMBL9538352 | 0.68 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL9535817 | 0.68 | PARP1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10PDE10A | |
| SCHEMBL10696099 | 0.68 | PARP1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10PDE10A | |
| SCHEMBL10696516 | 0.66 | PARP1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10PDE10A | |
| SCHEMBL9533229 | 0.65 | PARP1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10PDE10A | |
| SCHEMBL9532203 | 0.65 | KDM4E (0.65) | ALDH1A1KDM4EHPGDHSD17B10PARP1 | |
| SCHEMBL9831108 | 0.65 | PDE4B (0.42) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL9534712 | 0.64 | KDM4E (0.59) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL9532680 | 0.64 | KDM4E (0.63) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |