Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | CFB | P00751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10550617 | 0.84 | METAP2 (0.37) | METAP2METAP1NPY5RENPP1HTT | |
| SCHEMBL23452695 | 0.83 | METAP2 (0.40) | METAP2METAP1NPY5RENPP1HTT | |
| SCHEMBL14336558 | 0.78 | METAP2 (0.44) | METAP2METAP1NPY5RENPP1HTT | |
| SCHEMBL24859763 | 0.78 | METAP2 (0.37) | METAP2METAP1NPY5RENPP1HTT | |
| SCHEMBL23452690 | 0.77 | METAP2 (0.38) | METAP2METAP1NPY5RENPP1HTT | |
| SCHEMBL10552256 | 0.77 | METAP2 (0.38) | METAP2METAP1NPY5RENPP1HTT | |
| SCHEMBL2202798 | 0.75 | METAP2 (0.44) | METAP2METAP1NPY5RENPP1HTT | |
| SCHEMBL3014791 | 0.75 | HSD17B10 (0.57) | METAP2METAP1NPY5RHTTHSD17B10 | |
| SCHEMBL24859702 | 0.75 | METAP2 (0.37) | METAP2METAP1NPY5RENPP1HTT | |
| SCHEMBL23452686 | 0.73 | METAP2 (0.35) | METAP2METAP1NPY5RHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270885-A1 | Synthesis of purin-9-ylalkylenoxymethyl phosphonic acids | Bristol-Myers Squibb Company (US) | 1988-06-15 | — | — | EP | disclosed |