Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487826 | 1.00 | HPRT1 (0.58) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL31471980 | 1.00 | HPRT1 (0.58) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL12278069 | 1.00 | HPRT1 (0.58) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL420650 | 0.96 | ALDH1A1 (0.55) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| Benzene SCHEMBL28142112 | 0.94 | ALDH1A1 (0.52) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL31678978 | 0.94 | ALDH1A1 (0.52) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL27956417 | 0.92 | ALDH1A1 (0.50) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL22228584 | 0.90 | HPRT1 (0.52) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL22534718 | 0.89 | HPRT1 (0.50) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| Biphenyl SCHEMBL27935603 | 0.88 | ALDH1A1 (0.46) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4737301-A | Polycyclic thiophene lubricating oil additive and method of reducing coking tendencies of lubricating oils | EXXON CHEMICAL PATENTS INC. (US) | 1988-04-12 | — | — | US | claimed |
| EP-0250273-A2 | Polycyclic thiophene lubricating oil additive | EXXON CHEMICAL PATENTS INC. (US) | 1987-12-23 | — | — | EP | claimed |
| US-4737301-A | Polycyclic thiophene lubricating oil additive and method of reducing coking tendencies of lubricating oils | EXXON CHEMICAL PATENTS INC. (US) | 1988-04-12 | — | — | US | disclosed |
| EP-0250273-A2 | Polycyclic thiophene lubricating oil additive | EXXON CHEMICAL PATENTS INC. (US) | 1987-12-23 | — | — | EP | disclosed |
| US-4619756-A | THIOPHENE-CONTAINING POLYCONDENSED AROMATICNAPHTHENIC COMPOUNDS | EXXON CHEMICAL PATENTS INC. (US) | 1986-10-28 | — | — | US | disclosed |
| US-4618411-A | Additive combination and method for using it to inhibit deposit formation | EXXON CHEMICAL PATENTS INC. (US) | 1986-10-21 | — | — | US | disclosed |