SCHEMBL10695063

SCHEMBL10695063

O=C(O)CC(=S)C(=S)C(=S)CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.50
SRR Q9GZT4 1/20 0.50
GLRA1 P23415 1/20 0.39
SLC6A9 P48067 1/20 0.39
OR51E2 Q9H255 1/20 0.39
TSHR P16473 4/20 0.38
KDM4E B2RXH2 1/20 0.38
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 3/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
FFAR3 O14843 1/20 0.32
GABRR3 A8MPY1 1/20 0.30
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30
HDAC3 O15379 1/20 0.30
GABBR2 O75899 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9560314 0.80
Ammonia Solution, Strong SCHEMBL28082756 0.78 LDHA (0.47) LDHASRRGLRA1SLC6A9OR51E2
Malonic Acid SCHEMBL2131323 0.73
SCHEMBL28162358 0.72
Malonic Acid SCHEMBL8707685 0.69 LDHA (0.64) LDHASRRGLRA1SLC6A9OR51E2
SCHEMBL19585095 0.69 LDHA (0.53) LDHASRRGLRA1SLC6A9OR51E2
SCHEMBL8715816 0.69
SCHEMBL11332367 0.69
Malonic Acid SCHEMBL336 0.69
Malonic Acid SCHEMBL1332554 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0261274-A1 Process for the preparation of mercaptopropionacid C.F. Spiess & Sohn GmbH & Co. Chemische Fabrik (DE) 1988-03-30 EP disclosed