Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714542 | 0.98 | TSHR (0.52) | TSHRLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6775802 | 0.98 | TSHR (0.52) | TSHRLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9781700 | 0.98 | TSHR (0.52) | TSHRLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL11437952 | 0.98 | TSHR (0.52) | TSHRLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL3795395 | 0.96 | TSHR (0.54) | TSHRLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL3403179 | 0.94 | TSHR (0.56) | TSHRLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL214537 | 0.82 | — | — | |
| SCHEMBL13123489 | 0.81 | TSHR (0.50) | TSHRLMNAALDH1A1 | |
| SCHEMBL2824773 | 0.81 | TSHR (0.50) | TSHRLMNAALDH1A1 | |
| SCHEMBL11177812 | 0.81 | TSHR (0.50) | TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757085-A | Pharmaceuticals | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |