Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437952 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL9781700 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL6775802 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL10695420 | 0.98 | TSHR (0.50) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL3795395 | 0.98 | TSHR (0.54) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL3403179 | 0.92 | TSHR (0.56) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL214537 | 0.84 | — | — | |
| SCHEMBL13123489 | 0.83 | TSHR (0.50) | TSHRLMNAALDH1A1 | |
| SCHEMBL2824773 | 0.83 | TSHR (0.50) | TSHRLMNAALDH1A1 | |
| SCHEMBL11177812 | 0.83 | TSHR (0.50) | TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263481-B1 | PROCESS FOR THE PREPARATION OF ISOCYANATES | BAYER AG (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4745212-A | ESTERIFICATION OR AMIDATION OF ISOCYANATOCARBOXYL CHLORIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-17 | — | — | US | disclosed |
| EP-0263481-A2 | Process for the preparation of isocyanates | BAYER AG (DE) | 1988-04-13 | — | — | EP | disclosed |
| EP-0000023-B1 | OMEGA-SUBSTITUTED PENTYL UREAS, THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1980-07-23 | — | — | EP | disclosed |
| US-4188401-A | Combating fungi with 1-(ω-substituted pentyl)-3-(2-cyano-acetyl)-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-12 | — | — | US | disclosed |
| EP-0000023-A1 | Omega-substituted pentyl ureas, their preparation and their use as fungicides | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |
| US-4079147-A | Fungicidally active derivatives of carbamic acid oxime-esters of isonitrosocyanoacetic acid | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | disclosed |