Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20361871 | 0.95 | CA2 (0.50) | CA2CA1ZDHHC7MIFTSHR | |
| SCHEMBL4907463 | 0.95 | CA2 (0.50) | CA2CA1ZDHHC7MIFTSHR | |
| SCHEMBL10451509 | 0.95 | CA2 (0.50) | CA2CA1ZDHHC7MIFTSHR | |
| SCHEMBL11437950 | 0.89 | ZDHHC7 (0.53) | CA2CA1ZDHHC7MAPTHSD17B10 | |
| SCHEMBL11451874 | 0.89 | ZDHHC7 (0.53) | CA2CA1ZDHHC7MAPTHSD17B10 | |
| SCHEMBL1172986 | 0.88 | MIF (0.42) | CA2CA1ZDHHC7MIFTSHR | |
| SCHEMBL10201901 | 0.88 | MIF (0.42) | CA2CA1ZDHHC7MIFTSHR | |
| SCHEMBL9245515 | 0.88 | CA2 (0.44) | CA2CA1ZDHHC7MIFTSHR | |
| SCHEMBL23423085 | 0.86 | ZDHHC7 (0.39) | CA2CA1ZDHHC7MIFMAPT | |
| SCHEMBL21707116 | 0.86 | CA1 (0.37) | CA2CA1ZDHHC7MIFMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757085-A | Pharmaceuticals | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |