Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.63 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.63 |
| ▸ | PNMT | P11086 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129676 | 1.00 | OPRM1 (0.63) | OPRM1OPRL1PNMTKCNH2LMNA | |
| SCHEMBL10695431 | 1.00 | OPRM1 (0.63) | OPRM1OPRL1PNMTKCNH2LMNA | |
| Hydrochloric Acid SCHEMBL25378396 | 0.98 | OPRM1 (0.61) | OPRM1OPRL1PNMTKCNH2LMNA | |
| Hydrochloric Acid SCHEMBL31263899 | 0.98 | OPRM1 (0.61) | OPRM1OPRL1PNMTKCNH2LMNA | |
| SCHEMBL17782500 | 0.98 | OPRM1 (0.61) | OPRM1OPRL1PNMTKCNH2LMNA | |
| SCHEMBL30581918 | 0.98 | OPRM1 (0.61) | OPRM1OPRL1PNMTKCNH2LMNA | |
| Hydrochloric Acid SCHEMBL31263958 | 0.97 | OPRM1 (0.60) | OPRM1OPRL1PNMTKCNH2LMNA | |
| Hydrochloric Acid SCHEMBL25378009 | 0.97 | OPRM1 (0.60) | OPRM1OPRL1PNMTKCNH2LMNA | |
| Hydrochloric Acid SCHEMBL31263826 | 0.97 | OPRM1 (0.60) | OPRM1OPRL1PNMTKCNH2LMNA | |
| Hydrochloric Acid SCHEMBL25378709 | 0.97 | OPRM1 (0.60) | OPRM1OPRL1PNMTKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753952-A | ANALGESICS | DR. LO. ZAMBELETTI S.P.A. (IT) | 1988-06-28 | — | — | US | disclosed |