SCHEMBL10695434

SCHEMBL10695434

O=C(NCCO)c1cc(O)c2ccccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
KDM4E B2RXH2 4/20 0.57
MAPT P10636 1/20 0.57
CASP1 P29466 1/20 0.57
CASP7 P55210 1/20 0.57
HPGD P15428 3/20 0.51
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
CACNA1B Q00975 1/20 0.49
APBA1 Q02410 1/20 0.49
POLB P06746 1/20 0.45
HTT P42858 1/20 0.45
NQO2 P16083 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL161738 0.87 KDM4E (0.56) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL162959 0.84 SMN1; SMN2 (0.57) ALDH1A1KDM4EHPGDHTTHDAC3
SCHEMBL162795 0.83 BRD4 (0.45) ALDH1A1KDM4EMAPTHPGDMEN1
SCHEMBL10435868 0.82 NAAA (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL5668127 0.81 MAPT (0.56) ALDH1A1KDM4EMAPTHPGDMEN1
SCHEMBL160379 0.79 KMT2A (0.56) ALDH1A1KDM4EMAPTHPGDMEN1
SCHEMBL28344151 0.79 HDAC6 (0.52) KDM4ENQO2HSD17B10HDAC3HDAC4
SCHEMBL10670557 0.78 KDM4E (0.64) ALDH1A1KDM4EMAPTCASP1CASP7
SCHEMBL160412 0.78 PLK1 (0.50) ALDH1A1KDM4EMAPTHPGDNQO2
SCHEMBL1193527 0.78 HDAC1 (0.66) ALDH1A1KDM4EMAPTCASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0284378-A2 Light-fixable heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-09-28 EP disclosed
EP-0262953-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-04-06 EP disclosed