Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27892117 | 0.77 | SMN1; SMN2 (0.53) | KDM4ETDP1DHODHALDH1A1NPSR1 | |
| SCHEMBL27373458 | 0.75 | PTPN1 (0.45) | KDM4EALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL6054467 | 0.71 | SLC6A2 (0.43) | KDM4ETDP1ALDH1A1NPSR1CYP3A4 | |
| SCHEMBL3291158 | 0.71 | SLC6A4 (0.39) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL2627821 | 0.70 | KDM4E (0.59) | KDM4ETDP1DHODHALDH1A1NPSR1 | |
| SCHEMBL16508286 | 0.70 | CTNNB1 (0.45) | KDM4EALDH1A1MAPTTSHRLMNA | |
| SCHEMBL2559571 | 0.69 | SMN1; SMN2 (0.55) | KDM4ETDP1DHODHALDH1A1NPSR1 | |
| SCHEMBL25391378 | 0.69 | KDM4E (0.57) | KDM4ETDP1DHODHALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL17746066 | 0.69 | KDM4E (0.57) | KDM4ETDP1DHODHALDH1A1NPSR1 | |
| SCHEMBL3932427 | 0.69 | NAPRT (0.58) | KDM4ETDP1DHODHALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |