SCHEMBL16508286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4982136	0.78	CTNNB1 (0.50)	CTNNB1IRAK4KDM4EBCAT2ALDH1A1
	SCHEMBL4180612	0.76	IRAK4 (0.51)	CTNNB1IRAK4KDM4EBCAT2ALDH1A1
	SCHEMBL4553803	0.74	KDM4E (0.44)	CTNNB1IRAK4KDM4EBCAT2ALDH1A1
	SCHEMBL7197042	0.74	KDM4E (0.44)	CTNNB1IRAK4KDM4EBCAT2ALDH1A1
	SCHEMBL9542306	0.73	KDM4E (0.41)	CTNNB1IRAK4KDM4EBCAT2ALDH1A1
	SCHEMBL9618104	0.72	IDO1 (0.39)	KDM4EALDH1A1MAPTGAA
	SCHEMBL3292013	0.71	CA4 (0.40)	ALDH1A1HPGDTSHRPOLBLMNA
	SCHEMBL3291158	0.70	SLC6A4 (0.39)	KDM4EALDH1A1MAPTTSHR
	SCHEMBL6536715	0.70	PARP10 (0.39)	CTNNB1KDM4EALDH1A1MAPTTSHR
	SCHEMBL10695445	0.70	KDM4E (0.42)	KDM4EALDH1A1MAPTTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.