Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603282 | 0.80 | HRH3 (0.69) | KCNH2HRH3OPRM1DRD2SLC18A3 | |
| SCHEMBL1991909 | 0.79 | KCNH2 (0.44) | KCNH2HRH3OPRM1DRD2SLC18A3 | |
| SCHEMBL24291907 | 0.77 | KCNH2 (0.53) | KCNH2HRH3OPRM1DRD2SLC18A3 | |
| SCHEMBL20419215 | 0.77 | KCNH2 (0.53) | KCNH2HRH3OPRM1DRD2SLC18A3 | |
| SCHEMBL2661616 | 0.77 | KCNH2 (0.56) | KCNH2HRH3OPRM1DRD2SLC18A3 | |
| SCHEMBL10694280 | 0.77 | HTT (0.43) | KCNH2HRH3OPRM1SLC18A3CCR5 | |
| SCHEMBL27498941 | 0.77 | KCNH2 (0.60) | KCNH2HRH3OPRM1DRD2SLC18A3 | |
| SCHEMBL27498942 | 0.77 | KCNH2 (0.52) | KCNH2HRH3OPRM1DRD2SLC18A3 | |
| SCHEMBL13558661 | 0.75 | OPRM1 (0.58) | KCNH2HRH3OPRM1DRD2SLC18A3 | |
| SCHEMBL13225753 | 0.75 | KCNH2 (0.50) | KCNH2HRH3OPRM1DRD2SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |