Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 2/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18774942 | 0.80 | TSHR (0.38) | ANPEPALDH1A1TSHRMAPK1DNPEP | |
| SCHEMBL18774945 | 0.80 | TSHR (0.38) | ANPEPALDH1A1TSHRMAPK1DNPEP | |
| Hydrochloric Acid SCHEMBL8054309 | 0.78 | TSHR (0.36) | ANPEPALDH1A1TSHRMAPK1DNPEP | |
| SCHEMBL8041011 | 0.77 | ANPEP (0.30) | ANPEPDNPEP | |
| Hydrochloric Acid SCHEMBL8052324 | 0.76 | GMNN (0.31) | — | |
| SCHEMBL7337830 | 0.75 | ANPEP (0.33) | ANPEPALDH1A1TSHRMAPK1DNPEP | |
| SCHEMBL7270284 | 0.73 | ANPEP (0.33) | ANPEPALDH1A1TSHRMAPK1DNPEP | |
| SCHEMBL2953547 | 0.73 | TSHR (0.39) | ANPEPALDH1A1TSHRMAPK1DNPEP | |
| SCHEMBL10445391 | 0.72 | PSMB5 (0.41) | ANPEPALDH1A1DNPEPSLC7A5 | |
| SCHEMBL10354928 | 0.72 | ANPEP (0.35) | ANPEPALDH1A1TSHRMAPK1DNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275101-A2 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-07-20 | — | — | EP | disclosed |