Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 6/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 2/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18774942 | 0.78 | TSHR (0.38) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL18774945 | 0.78 | TSHR (0.38) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL17897965 | 0.78 | ANPEP (0.33) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| Hydrochloric Acid SCHEMBL8054309 | 0.76 | TSHR (0.36) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL7437500 | 0.76 | ANPEP (0.33) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL7270284 | 0.76 | ANPEP (0.33) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL10355433 | 0.74 | ANPEP (0.35) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| Hydrochloric Acid SCHEMBL7439334 | 0.74 | GMNN (0.33) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL10354928 | 0.74 | ANPEP (0.35) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL7434781 | 0.74 | TSHR (0.34) | TSHRALDH1A1MAPK1ANPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767825-B2 | 2,2′,6,6′-tetraoxazolinyl biphenyl ligand and method for preparing the same | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2010-08-03 | — | — | US | disclosed |
| US-20090043104-A1 | 2,2',6,6' - TETRAOXAZOLINYL BIPHENYL LIGAND AND METHOD FOR PREPARING THE SAME | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043104-A1 | 2,2',6,6' - TETRAOXAZOLINYL BIPHENYL LIGAND AND METHOD FOR PREPARING THE SAME | IP6K2, PIP4K2C, IP6K3 | TSHR 230/4885ALDH1A1 4305/4885MAPK1 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.