Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28284858 | 0.94 | MAPT (0.57) | MAPTKMT2AFFAR4FFAR1CES2 | |
| SCHEMBL28169093 | 0.91 | MAPT (0.54) | MAPTKMT2AFFAR4FFAR1CES2 | |
| SCHEMBL31695317 | 0.91 | MAPT (0.48) | MAPTKMT2AFFAR4FFAR1CES2 | |
| SCHEMBL12060078 | 0.89 | MAPT (0.57) | MAPTKMT2AFFAR4FFAR1CES2 | |
| SCHEMBL1121772 | 0.89 | ALDH1A1 (0.44) | MAPTKMT2ANFKB1 | |
| SCHEMBL11222883 | 0.87 | MAPT (0.43) | MAPTKMT2AFFAR4FFAR1NFKB1 | |
| SCHEMBL23735963 | 0.85 | MAPT (0.42) | MAPTKMT2AFFAR4FFAR1NFKB1 | |
| SCHEMBL8620850 | 0.84 | MAPT (0.45) | MAPTKMT2AFFAR4FFAR1CES2 | |
| SCHEMBL15544260 | 0.84 | KMT2A (0.56) | MAPTKMT2AFFAR4FFAR1CES2 | |
| SCHEMBL8896878 | 0.83 | KMT2A (0.59) | MAPTKMT2AFFAR4FFAR1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719132-A | AUTOMOBILES | PPG INDUSTRIES, INC. (US) | 1988-01-12 | — | — | US | disclosed |