⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29775436 | 0.81 | — | — | |
| SCHEMBL2179497 | 0.81 | — | — | |
| SCHEMBL8418376 | 0.81 | — | — | |
| SCHEMBL4710125 | 0.81 | — | — | |
| SCHEMBL27463859 | 0.79 | — | — | |
| SCHEMBL16994166 | 0.79 | — | — | |
| SCHEMBL27737191 | 0.79 | — | — | |
| SCHEMBL10697833 | 0.79 | — | — | |
| SCHEMBL27478949 | 0.79 | — | — | |
| SCHEMBL7155602 | 0.79 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10857211-B2 | Genomic instability markers in Fanconi anemia | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2020-12-08 | — | — | US | disclosed |
| US-20170100462-A1 | GENOMIC INSTABILITY MARKERS IN FANCONI ANEMIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-04-13 | — | — | US | disclosed |
| WO-2015179779-A1 | GENOMIC INSTABILITY MARKERS IN FANCONI ANEMIA | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2015-11-26 | — | — | WO | disclosed |
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |
| US-4062947-A | Di-N-alkylaminoglycosides, methods for their manufacture and novel intermediates useful therein, method for their use as antibacterial agents and pharmaceutical compositions useful therefor | SCHERING CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |