Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684650 | 0.86 | HRH3 (0.68) | HRH3 | |
| SCHEMBL7684647 | 0.82 | HRH3 (0.45) | HRH3MAP3K5APP | |
| SCHEMBL2086415 | 0.71 | RXFP1 (0.47) | MAP3K5APP | |
| SCHEMBL10571006 | 0.71 | HRH3 (0.67) | HRH3 | |
| SCHEMBL10695750 | 0.69 | HRH3 (0.44) | HRH3MAP3K5APP | |
| SCHEMBL7682230 | 0.69 | HRH3 (0.68) | HRH3 | |
| SCHEMBL1500236 | 0.68 | KDM4E (0.64) | — | |
| SCHEMBL1500262 | 0.68 | PIK3CG (0.51) | HRH3MAP3K5APP | |
| SCHEMBL10571000 | 0.67 | HRH3 (0.44) | HRH3 | |
| SCHEMBL7684986 | 0.66 | HRH3 (1.00) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727145-A | LOCAL ANESTHETICS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |