Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692538 | 0.87 | ALDH1A1 (0.42) | HTR1BALDH1A1CYP1A2CYP2A6HPGD | |
| SCHEMBL10693274 | 0.86 | HTR1B (0.47) | HTR1BALDH1A1CYP1A2CYP2A6HPGD | |
| SCHEMBL10690407 | 0.85 | HTR1B (0.56) | HTR1BKCNA3HTR2ASSTR2SSTR4 | |
| SCHEMBL10692959 | 0.83 | HTR1B (0.56) | HTR1BALDH1A1CYP1A2CYP2A6HPGD | |
| SCHEMBL10692940 | 0.83 | HTR1B (0.54) | HTR1BALDH1A1CYP1A2HSD17B10KCNA3 | |
| SCHEMBL10688833 | 0.83 | HTR1B (0.54) | HTR1BALDH1A1CYP1A2HSD17B10KCNA3 | |
| SCHEMBL10692231 | 0.83 | HTR1B (0.54) | HTR1BALDH1A1CYP1A2HSD17B10KCNA3 | |
| SCHEMBL10695724 | 0.83 | HTR1B (0.54) | HTR1BALDH1A1CYP1A2HSD17B10KCNA3 | |
| SCHEMBL10693528 | 0.83 | HTR1B (0.54) | HTR1BALDH1A1CYP1A2HSD17B10KCNA3 | |
| SCHEMBL10692059 | 0.83 | HTR1B (0.54) | HTR1BALDH1A1CYP1A2HSD17B10KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |