SCHEMBL10696024

SCHEMBL10696024

Cc1ccc(O)c(CCCC=O)c1C=O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.36
CDK1 P06493 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP3A4 P08684 2/20 0.33
MAPT P10636 2/20 0.33
USP2 O75604 1/20 0.32
MAOB P27338 3/20 0.32
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7519840 0.83 HIF1A (0.36) CDK1HIF1AMAPTTRPV1
SCHEMBL5861264 0.75 CDK1 (0.41) ERN1CDK1HIF1A
SCHEMBL5861293 0.74 HIF1A (0.42) ERN1HIF1AMAPT
SCHEMBL7514297 0.74 SCN5A (0.33)
SCHEMBL7717189 0.72 ERN1 (0.49) ERN1CYP3A4MAPTUSP2
SCHEMBL31351301 0.72 ERN1 (0.49) ERN1CYP3A4MAPTUSP2
SCHEMBL4650198 0.70 CYP3A4 (0.44) ERN1CYP3A4MAPTUSP2
SCHEMBL3975489 0.70 ERN1 (0.43) ERN1CYP3A4MAPTUSP2MAOB
SCHEMBL29950973 0.70 ERN1 (0.43) ERN1CYP3A4MAPTUSP2MAOB
SCHEMBL5862298 0.70 CDK1 (0.44) ERN1CDK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0266654-A2 Light sensitive composition, material containing it and process for producing positive or negative relief copies by using this material HOECHST AKTIENGESELLSCHAFT (DE) 1988-05-11 EP disclosed