SCHEMBL7519840

SCHEMBL7519840

Cc1ccc(O)c(CCCC=O)c1C

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.36
MAOA P21397 1/20 0.33
PTGS1 P23219 1/20 0.33
SCN5A Q14524 1/20 0.33
TRPA1 O75762 1/20 0.32
ATM Q13315 1/20 0.32
MAPT P10636 1/20 0.32
CDK1 P06493 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
TSHR P16473 1/20 0.31
NQO1 P15559 1/20 0.31
TYR P14679 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7514297 0.91 SCN5A (0.33) MAOAPTGS1SCN5ATRPA1ATM
SCHEMBL10696024 0.83 ERN1 (0.36) HIF1AMAPTCDK1TRPV1
SCHEMBL7518549 0.79 TRPA1 (0.35) MAOAPTGS1SCN5ATRPA1ATM
SCHEMBL5861293 0.77 HIF1A (0.42) HIF1ATRPA1ATMMAPT
SCHEMBL983815 0.77 HPGD (0.48) TRPA1ATMTYR
SCHEMBL30945773 0.77 HPGD (0.48) TRPA1ATMTYR
SCHEMBL980191 0.76 TYR (0.53) HIF1APTGS1MAPTTSHRTYR
SCHEMBL980079 0.75 CNR1 (0.41) TRPA1ATMTSHRTYR
SCHEMBL30945836 0.75 CNR1 (0.41) TRPA1ATMTSHRTYR
SCHEMBL983680 0.74 TYR (0.56) HIF1APTGS1MAPTTSHRTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0784528-B1 ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT MINNESOTA MINING & MFG (US) 2002-01-30 EP claimed
US-5725617-A Abrasive articles with encapsulated lubricant MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-10 US claimed
EP-0784528-A1 ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-23 EP claimed
WO-1996011085-A1 ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-18 WO claimed
EP-0784528-B1 ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT MINNESOTA MINING & MFG (US) 2002-01-30 EP disclosed
US-5725617-A Abrasive articles with encapsulated lubricant MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-10 US disclosed
EP-0784528-A1 ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-23 EP disclosed
WO-1996011085-A1 ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-18 WO disclosed