Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179834 | 1.00 | TSHR (0.56) | TSHRKDM4ECPB1LDHASRR | |
| SCHEMBL12101265 | 0.75 | EGLN1 (0.40) | TSHRKDM4ECPB1LDHASRR | |
| SCHEMBL33410 | 0.74 | TSHR (0.59) | TSHRKDM4ECPB1LDHASRR | |
| SCHEMBL28123688 | 0.74 | TSHR (0.59) | TSHRKDM4ECPB1LDHASRR | |
| SCHEMBL9567017 | 0.74 | TSHR (0.59) | TSHRKDM4ECPB1LDHASRR | |
| SCHEMBL707103 | 0.74 | TSHR (0.59) | TSHRKDM4ECPB1LDHASRR | |
| SCHEMBL6365923 | 0.74 | TSHR (0.59) | TSHRKDM4ECPB1LDHASRR | |
| SCHEMBL4115859 | 0.74 | TSHR (0.65) | TSHRKDM4ECPB1LDHASRR | |
| SCHEMBL1234795 | 0.74 | TSHR (0.65) | TSHRKDM4ECPB1LDHASRR | |
| SCHEMBL19032421 | 0.72 | TSHR (0.56) | TSHRKDM4ECPB1LDHASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283127-A1 | Surgical staple | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-09-21 | — | — | EP | disclosed |