SCHEMBL1234795

SCHEMBL1234795

NC(=O)/C=C(/CC(=O)O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
KDM4E B2RXH2 1/20 0.65
CPB1 P15086 1/20 0.47
LDHA P00338 2/20 0.38
SRR Q9GZT4 1/20 0.38
CYP2C19 P33261 1/20 0.37
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ABAT P80404 1/20 0.33
LDHB P07195 1/20 0.32
RECQL P46063 1/20 0.31
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GLRA1 P23415 1/20 0.30
SLC6A9 P48067 1/20 0.30
OR51E2 Q9H255 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4115859 1.00 TSHR (0.65) TSHRKDM4ECPB1LDHASRR
SCHEMBL7771088 0.92 TSHR (0.52) TSHRKDM4ECPB1LDHASRR
SCHEMBL7771087 0.92 TSHR (0.52) TSHRKDM4ECPB1LDHASRR
SCHEMBL8209991 0.85 KDM4E (0.46) TSHRKDM4ECPB1LDHAABAT
SCHEMBL30173709 0.85 KDM4E (0.46) TSHRKDM4ECPB1LDHAABAT
SCHEMBL24180793 0.81 KDM4E (0.43) TSHRKDM4ECPB1ALOX15ABAT
Aconitic Acid SCHEMBL22334 0.79 TSHR (1.00) TSHRKDM4ECPB1LDHASRR
SCHEMBL7771390 0.79 TSHR (0.39) TSHRKDM4ECPB1LDHACYP2C19
SCHEMBL7771392 0.79 TSHR (0.39) TSHRKDM4ECPB1LDHACYP2C19
Aconitic Acid SCHEMBL219037 0.79 TSHR (1.00) TSHRKDM4ECPB1LDHASRR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 643 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3641832-B1 NUCLEIC ACID NANOCAPSULES FOR DRUG DELIVERY AND TARGETED GENE KNOCKDOWN UNIV CONNECTICUT (US) 2024-09-11 EP claimed
EP-0080451-B1 METHOD AND COMPOSITION FOR DIENE RUBBER TREATMENT MONSANTO COMPANY (US) 1985-09-18 EP claimed
US-20260144888-A1 USE OF A LIQUID AQUEOUS COMPOSITION FOR SOLUBILIZATION AND STABILIZATION OF AN ANTIBODY-DRUG CONJUGATE PIERRE FABRE MEDICAMENT (FR) 2026-05-28 US disclosed
EP-4748862-A2 HETERODIMERIC PROTEINS Xencor, Inc. (US) 2026-05-27 EP disclosed
EP-3620473-B1 NOVEL HETERODIMERIC PROTEINS XENCOR INC (US) 2026-05-27 EP disclosed
EP-4748856-A2 COMPOSITIONS AND METHODS FOR TREATING CANCER WITH SELF-DRIVING CHIMERIC ANTIGEN RECEPTORS Lentigen Technology, Inc. (US) 2026-05-27 EP disclosed
US-20260139073-A1 Antigen Binding Proteins GLAXO GROUP LIMITED (GB) 2026-05-21 US disclosed
EP-4739396-A1 HUMANIZED 40H3 ANTIBODY The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2026-05-13 EP disclosed
US-12624104-B2 Compositions and methods for treating cancer with anti-CD19 immunotherapy LENTIGEN TECHNOLOGY, INC. (US) 2026-05-12 US disclosed
EP-4737482-A1 HUMANIZED ANTI-MYCT1 ANTIBODY AND USE THEREOF Atheon Bio, Inc. (KR) 2026-05-06 EP disclosed
EP-3817770-B1 ANTI-STEAP1 ANTIGEN-BINDING PROTEIN AMGEN INC (US) 2026-05-06 EP disclosed
US-11248054-B2 Anti-IL1RAP antibodies and antibody drug conjugates BLUEFIN BIOMEDICINE, INC. (US) 2022-02-15 US disclosed
WO-2022031652-A1 ANTI-CD228 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES SEAGEN INC. (US) 2022-02-10 WO disclosed
EP-2099823-B2 VARIANT TARGET BINDING AGENTS AND USES THEREOF SEAGEN INC (US) 2022-02-09 EP disclosed
US-20220033503-A1 Anti PD-L1 Conjugates for Treating Tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2022-02-03 US disclosed
US-20220031859-A1 HERBOXIDIENE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2022-02-03 US disclosed
EP-2609932-B1 VARIANT TARGET BINDING AGENTS AND USES THEREOF SEAGEN INC (US) 2022-02-02 EP disclosed
US-11230610-B2 Bivalent antibodies masked by coiled coils SEAGEN INC. (US) 2022-01-25 US disclosed
US-20110060123-A1 CHARGE CONVERSIONAL TERNARY POLYPLEX THE UNIVERSITY OF TOKYO (JP) 2011-03-10 US disclosed
EP-2284210-A1 CHARGE CONVERSIONAL TERNARY POLYPLEX The University of Tokyo (JP) 2011-02-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110060123-A1 CHARGE CONVERSIONAL TERNARY POLYPLEX PARN, PARG, NCAPD2 TSHR 4445/4885KDM4E 3902/4885CPB1 738/4885
US-20220033503-A1 Anti PD-L1 Conjugates for Treating Tumors CD274, PDCD1LG2, PDCD1 TSHR 1768/4885KDM4E 1009/4885CPB1 3570/4885
US-20220031859-A1 HERBOXIDIENE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE CD74, HPGD, HLA-DRB1 TSHR 2959/4885KDM4E 1529/4885CPB1 3612/4885
US-20260144888-A1 USE OF A LIQUID AQUEOUS COMPOSITION FOR SOLUBILIZATION AND STABILIZATION OF AN ANTIBODY-DRUG CONJUGATE IGF1R, CD44, MUC1 TSHR 60/4885KDM4E 4172/4885CPB1 3689/4885
US-11248054-B2 Anti-IL1RAP antibodies and antibody drug conjugates IL1RN, IL1R1, IL1A TSHR 922/4885KDM4E 4317/4885CPB1 2772/4885
US-11230610-B2 Bivalent antibodies masked by coiled coils COIL, CRYAB, UACA TSHR 1813/4885KDM4E 2917/4885CPB1 73/4885
US-20260139073-A1 Antigen Binding Proteins TNFSF11, TNFSF10, CD40 TSHR 870/4885KDM4E 79/4885CPB1 1201/4885
US-12624104-B2 Compositions and methods for treating cancer with anti-CD19 immunotherapy CD2, CD22, CD4 TSHR 699/4885KDM4E 1536/4885CPB1 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.