Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666606 | 0.93 | TSHR (0.30) | — | |
| SCHEMBL10691939 | 0.92 | ABCB1 (0.35) | — | |
| SCHEMBL10688684 | 0.86 | KMT2A (0.31) | — | |
| SCHEMBL10696062 | 0.86 | ABCB1 (0.33) | SLC6A1TRIM24ERAP1GFER | |
| SCHEMBL10695887 | 0.86 | ABCB1 (0.34) | — | |
| SCHEMBL10693262 | 0.85 | ABCB1 (0.34) | — | |
| SCHEMBL10697691 | 0.85 | — | — | |
| SCHEMBL9668732 | 0.79 | ABCB1 (0.42) | — | |
| SCHEMBL10691936 | 0.78 | ABCB1 (0.40) | — | |
| SCHEMBL9666854 | 0.77 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792559-A | 1,2,3,4-tetrahydroquinoline substituted 5-aminopentanenitrile compounds and their use as calcium modulators | ADIR ET COMPAGNIE (FR) | 1988-12-20 | — | — | US | disclosed |