Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAP1LC3B | Q9GZQ8 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692343 | 0.79 | ESR2 (0.34) | ESR2PLAUALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10873431 | 0.78 | ESR2 (0.45) | ESR2NPC1RAB9APOLBNOTUM | |
| SCHEMBL428432 | 0.76 | MAP1LC3B (0.55) | MAPTGAAMAP1LC3BSMN1; SMN2POLB | |
| SCHEMBL8594892 | 0.73 | SPHK1 (0.47) | MAPTESR2ALDH1A1POLBNOTUM | |
| SCHEMBL10672428 | 0.72 | MAPT (0.77) | MAPTGAAMAP1LC3BESR2PLAU | |
| SCHEMBL29234046 | 0.71 | MAPT (0.50) | MAPTGAAMAP1LC3BESR2PLAU | |
| SCHEMBL425308 | 0.71 | POLB (0.58) | MAPTGAAMAP1LC3BRAB9AALDH1A1 | |
| SCHEMBL5612 | 0.71 | BRD4 (0.53) | MAPTGAAMAP1LC3BESR2NPC1 | |
| SCHEMBL426339 | 0.71 | MAP1LC3B (0.53) | MAPTGAAMAP1LC3BSMN1; SMN2ALPL | |
| SCHEMBL23185740 | 0.71 | ESR2 (0.59) | ESR2NPC1RAB9APOLBNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253501-A2 | N-disubstituted cycloalkylmethyl amines useful as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-20 | — | — | EP | disclosed |