MAP1LC3B

Microtubule-associated protein 1 light chain 3 beta · Q9GZQ8 · MAP1LC3B on Sugi Atlas →

24,194 patent compounds predicted against MAP1LC3B, 12,505 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1779869 SCHEMBL1779869 1.00 11/20
SCHEMBL1780428 SCHEMBL1780428 0.69 10/20
SCHEMBL1781059 SCHEMBL1781059 0.59 10/20
SCHEMBL193131 SCHEMBL193131 0.44 10/20
SCHEMBL1780317 SCHEMBL1780317 1.00 9/20
SCHEMBL1780581 SCHEMBL1780581 1.00 7/20
SCHEMBL1781367 SCHEMBL1781367 1.00 7/20
SCHEMBL1781754 SCHEMBL1781754 1.00 7/20
SCHEMBL1097880 SCHEMBL1097880 0.56 7/20
SCHEMBL423680 SCHEMBL423680 0.53 6/20
SCHEMBL1781501 SCHEMBL1781501 0.52 6/20
SCHEMBL1424432 SCHEMBL1424432 0.46 6/20
SCHEMBL955853 SCHEMBL955853 0.44 6/20
SCHEMBL476989 SCHEMBL476989 0.60 5/20
Lenalidomide Lenalidomide (SCHEMBL1486013) 0.50 5/20
SCHEMBL1493251 SCHEMBL1493251 0.48 5/20
SCHEMBL1424683 SCHEMBL1424683 0.47 5/20
SCHEMBL960281 SCHEMBL960281 0.46 5/20
SCHEMBL1520716 SCHEMBL1520716 0.41 5/20
SCHEMBL464519 SCHEMBL464519 0.54 4/20

Clinical trials — most relevant to MAP1LC3B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Motor Function Efficacy of Pharmacological Treatments Targeting Energy Metabolism, in Parkinson's Patients PHASE4UNKNOWN
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Efficacy of Lithium Against Chemotherapy Induced Neutropenia in Breast Cancer Patients PHASE3COMPLETED
Effects of Cannabidiol (CBD) on the Activation of Autophagy and Inflammation Genes, Functional Consequences in Virologically Controlled HIV-infected Patients PHASE2COMPLETED
LCL161 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis PHASE2COMPLETED
FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer PHASE1/PHASE2COMPLETED
Clostridium Butyricum in Stenosing Crohn's Desease PHASE1/PHASE2NOT_YET_RECRUITING
Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease. PHASE1COMPLETED
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Ricolinostat, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable or Metastatic Cholangiocarcinoma PHASE1WITHDRAWN
Far Infrared Irradiation for the Management, Control and Treatment of Frontotemporal Dementia PHASE1UNKNOWN
Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction EARLY_PHASE1RECRUITING
Immunohistochemical Assessment of Programmed Death ligand1 and LC3B in GBM nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Molecular Profile of the Evolution of Inclusion Body Myositis nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
Autophagy Markers in Endometrial Polyps nanCOMPLETED
Correlation Between Autophagy-related Proteins and Inflammatory Markers in Hemodialysis Patients nanCOMPLETED
Muscle Insulin Resistance in Aging (Mirage) nanACTIVE_NOT_RECRUITING
Fasting, Exercise, and Diet to Activate Autophagy in Depression nanNOT_YET_RECRUITING
Time Course for Fasting-induced Autophagy in Humans nanWITHDRAWN
Evaluation of Serum Autophagic Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Individuals nanENROLLING_BY_INVITATION
Evaluation of a Novel PET Radioligand to Image OGA nanCOMPLETED
Neurofilament Light- Chain in Ataxia Telangiectasia nanUNKNOWN
Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective nanCOMPLETED
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure nanCOMPLETED
Autophagy/Apoptosis Balance in Placental Vascular Pathologies nanRECRUITING
Strong Evidence: Digitally Delivered Exercise in Older Adults nanACTIVE_NOT_RECRUITING
Robotic vs. Traditional Verticalization in Patients With Severe Acquired Brain Injury: a Randomized Controlled Trial nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a MAP1LC3B binder may also engage these)

ProteinNameSimilarity
O41515 1.000 O41515 →
Q9CQV6 1.000 Q9CQV6 →
Q6XVN8 1.000 Q6XVN8 →
A6NCE7 1.000 A6NCE7 →
Q91VR7 1.000 Q91VR7 →
Q2HJ23 1.000 Q2HJ23 →
MAP1LC3A Microtubule-associated protein 1 light chain 3 alpha 1.000 landscape →
A2XXR7 1.000 A2XXR7 →
Q9XEB5 1.000 Q9XEB5 →
Q6CMF8 1.000 Q6CMF8 →
Q2RBS4 0.999 Q2RBS4 →
Q23536 0.999 Q23536 →
Q5QFG1 0.998 Q5QFG1 →
Q62625 0.998 Q62625 →
Q8S927 0.998 Q8S927 →
Q8S926 0.998 Q8S926 →
P0C075 0.998 P0C075 →
Q9BY60 0.997 Q9BY60 →
Q8S925 0.997 Q8S925 →
Q755X2 0.997 Q755X2 →
Q9DCD6 0.997 Q9DCD6 →
Q6Z1D5 0.997 Q6Z1D5 →
Q9LRP7 0.997 Q9LRP7 →
Q8IJK2 0.997 Q8IJK2 →
GABARAP Gamma-aminobutyric acid receptor-associated protein 0.996 landscape →
Q8MK68 0.996 Q8MK68 →
P0CO54 0.996 P0CO54 →
O94272 0.996 O94272 →
Q7XPR1 0.996 Q7XPR1 →
P38182 0.996 P38182 →