SCHEMBL10696310

SCHEMBL10696310

Nc1ccc(S(=O)(=O)NCCS(=O)(=O)O)cc1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.63
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA9 Q16790 3/20 0.50
CA12 O43570 2/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
CYP3A4 P08684 4/20 0.46
ALDH1A1 P00352 4/20 0.46
TSHR P16473 2/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
CASP1 P29466 1/20 0.46
RECQL P46063 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11682894 0.92 CYP2D6 (0.52) CYP2D6CA1CA2CA9CA12
SCHEMBL9444696 0.86 CYP2D6 (0.69) CYP2D6CA1CA2CA9CA12
SCHEMBL11516148 0.83 CYP2D6 (0.59) CYP2D6CA1CA2CA9CA12
SCHEMBL11519780 0.82 CYP2D6 (0.63) CYP2D6CA1CA2CA9CA12
SCHEMBL12010052 0.81 ALDH1A1 (0.56) CA1CA2CA9CA12CA4
SCHEMBL11518471 0.79 CYP2D6 (0.58) CYP2D6ALDH1A1MEN1KMT2AHTT
SCHEMBL11521809 0.79 CYP2D6 (0.58) CYP2D6CA1CA2ALDH1A1TSHR
SCHEMBL11689794 0.78 CA1 (0.49) CYP2D6CA1CA2CA9CA12
SCHEMBL11516144 0.78 CYP2D6 (1.00) CYP2D6CA1CA2CA9CA12
SCHEMBL10688912 0.78 CYP2D6 (0.49) CYP2D6CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
US-4180503-A FOR DYEING POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-12-25 US disclosed
US-4124581-A FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST BAYER AKTIENGESELLSCHAFT (DE) 1978-11-07 US disclosed
US-4060521-A POLYAMIDE BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 US disclosed