Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28521954 | 0.83 | KDM4E (0.43) | KDM4EHSD17B10GAATSHRSMN1; SMN2 | |
| SCHEMBL17781294 | 0.82 | KDM4E (0.49) | KDM4EHSD17B10GAATSHRSMN1; SMN2 | |
| SCHEMBL18208732 | 0.76 | GABRP (0.44) | KDM4EHSD17B10GAATSHRSMN1; SMN2 | |
| SCHEMBL17797439 | 0.75 | KDM4E (0.40) | KDM4EHSD17B10GAATSHRSMN1; SMN2 | |
| SCHEMBL4436848 | 0.75 | HSD17B10 (0.48) | KDM4EHSD17B10GAATSHRSMN1; SMN2 | |
| SCHEMBL29116932 | 0.74 | IRAK4 (0.39) | KDM4EHSD17B10ALDH1A1TDP1HPGD | |
| SCHEMBL29116929 | 0.74 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1TDP1HPGD | |
| SCHEMBL17781051 | 0.74 | PDE2A (0.54) | KDM4EHSD17B10GAATSHRSMN1; SMN2 | |
| SCHEMBL310126 | 0.74 | PDE2A (0.59) | KDM4EALDH1A1TDP1PDE2A | |
| SCHEMBL32679866 | 0.73 | KDM4E (0.50) | KDM4EHSD17B10GAATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3292107-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2018-03-14 | — | — | EP | disclosed |
| WO-2016177658-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-11-10 | — | — | WO | disclosed |
| EP-0254495-A2 | Beta-Lactam compound, method for preparing the same, medicinal composition for bacterially infectious disease therapy containing the same and intermediates for synthesis of the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | disclosed |