Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diallate SCHEMBL10696405 | 1.00 | TDP1 (0.34) | TDP1L3MBTL1SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL4888977 | 0.83 | IDO1 (0.41) | TDP1L3MBTL1SMN1; SMN2IDO1HDAC3 | |
| SCHEMBL65715 | 0.83 | IDO1 (0.41) | TDP1L3MBTL1SMN1; SMN2IDO1HDAC3 | |
| Thiobencarb SCHEMBL8337284 | 0.80 | ALDH1A1 (0.39) | TDP1L3MBTL1SMN1; SMN2IDO1KMT2A | |
| SCHEMBL11859462 | 0.79 | KMT2A (0.45) | TDP1L3MBTL1SMN1; SMN2IDO1KMT2A | |
| Diallate SCHEMBL116715 | 0.78 | POLB (0.31) | — | |
| Diallate SCHEMBL8534983 | 0.78 | POLB (0.31) | — | |
| Diallate SCHEMBL148827 | 0.78 | POLB (0.31) | — | |
| Diallate SCHEMBL1873360 | 0.78 | POLB (0.31) | — | |
| SCHEMBL11792567 | 0.75 | TDP1 (0.44) | TDP1L3MBTL1SMN1; SMN2IDO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4749406-A | Quinoline derivatives and compositions thereof for the protection of cultivated plants | CIBA-GEIGY CORPORATION (US) | 1988-06-07 | — | — | US | disclosed |
| US-4483707-A | PLANT SAFTENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-11-20 | — | — | US | disclosed |