Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806386 | 0.84 | PDK1 (0.54) | KMT2AMEN1KAT2BPDK1PDK2 | |
| SCHEMBL14247107 | 0.84 | KMT2A (0.49) | KMT2AMEN1KAT2BPDK1PDK2 | |
| SCHEMBL10868680 | 0.84 | MEN1 (0.49) | KMT2AMEN1KAT2BPDK1PDK2 | |
| SCHEMBL677655 | 0.81 | MAPK1 (0.55) | KMT2AMEN1KAT2BPDK1PDK2 | |
| SCHEMBL13729342 | 0.80 | KMT2A (0.53) | KMT2AMEN1PDK1PDK2PDK3 | |
| SCHEMBL24187914 | 0.75 | PDK1 (0.55) | KMT2AMEN1PDK1PDK2PDK3 | |
| SCHEMBL10359712 | 0.75 | MAPK1 (0.53) | KMT2AMEN1KAT2BPDK1PDK2 | |
| SCHEMBL22716911 | 0.74 | KAT2B (0.56) | KMT2AMEN1KAT2BPDK1PDK2 | |
| SCHEMBL11657337 | 0.74 | PDK1 (0.54) | KMT2AMEN1PDK1PDK2PDK3 | |
| SCHEMBL29631845 | 0.74 | MAPK1 (0.47) | KMT2AMEN1KAT2BPDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |