Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157238 | 0.81 | RAPGEF4 (0.44) | HSD17B10RAPGEF4ALDH1A1GAAMAPT | |
| SCHEMBL11240417 | 0.79 | RAPGEF4 (0.42) | HSD17B10RAPGEF4ALDH1A1GAAMAPT | |
| SCHEMBL5677336 | 0.78 | HSD17B10 (0.63) | HSD17B10RAPGEF4ALDH1A1GAAMAPT | |
| SCHEMBL31330205 | 0.76 | RAPGEF4 (0.47) | HSD17B10RAPGEF4ALDH1A1GAAMAPT | |
| SCHEMBL158166 | 0.76 | RAPGEF4 (0.47) | HSD17B10RAPGEF4ALDH1A1GAAMAPT | |
| SCHEMBL1606275 | 0.76 | MAPT (0.57) | HSD17B10RAPGEF4ALDH1A1GAAMAPT | |
| SCHEMBL31184477 | 0.76 | RAPGEF4 (0.50) | HSD17B10RAPGEF4ALDH1A1GAAMAPT | |
| SCHEMBL487024 | 0.76 | RAPGEF4 (0.50) | HSD17B10RAPGEF4ALDH1A1GAAMAPT | |
| SCHEMBL7549551 | 0.75 | HSD17B10 (0.46) | HSD17B10RAPGEF4ALDH1A1GAAMAPT | |
| SCHEMBL156095 | 0.75 | HSD17B10 (0.49) | HSD17B10RAPGEF4ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271656-A1 | Reactive amino alkoxy-triphene dioxazine dyes | BAYER AG (DE) | 1988-06-22 | — | — | EP | disclosed |