SCHEMBL10696507

SCHEMBL10696507

Cc1nc2c(-c3ccccc3)cccc2[nH]1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 7/20 0.49
PARP1 P09874 1/20 0.49
DHODH Q02127 4/20 0.47
ADORA3 P0DMS8 1/20 0.45
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
DRD2 P14416 1/20 0.44
DRD4 P21917 1/20 0.44
DRD3 P35462 1/20 0.44
ALDH1A1 P00352 1/20 0.43
PDE10A Q9Y233 1/20 0.43
CNR1 P21554 1/20 0.43
MGAM O43451 3/20 0.43
GAA P10253 3/20 0.43
SI P14410 3/20 0.43
MGAM2 Q2M2H8 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17263813 0.88 PARP1 (0.47) CNR2PARP1DHODHKDM4ESMN1; SMN2
SCHEMBL20936149 0.87 PARP1 (0.56) PARP1KDM4EHPGDSMN1; SMN2DRD2
SCHEMBL712492 0.85 MGAM (0.55) CNR2PARP1DHODHKDM4ESMN1; SMN2
SCHEMBL8589063 0.83 PARP1 (0.48) CNR2PARP1DHODHALDH1A1MGAM
SCHEMBL14959119 0.82 MGAM (0.57) PARP1DHODHADORA3MGAMGAA
SCHEMBL1170898 0.81 DHODH (0.54) CNR2PARP1DHODHKDM4ESMN1; SMN2
SCHEMBL8816910 0.80 MGAM (0.60) DHODHHPGDSMN1; SMN2ALDH1A1PDE10A
SCHEMBL31027957 0.80 DHODH (0.59) CNR2PARP1DHODHALDH1A1PDE10A
SCHEMBL19217456 0.79 DHODH (0.44) PARP1DHODHADORA3ADORA2AADORA1
SCHEMBL14959118 0.79 MGAM (0.59) CNR2PARP1DHODHDRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109566351-B Culture medium for improving germination rate 上海派布利克贸易有限公司 2021-10-26 CN disclosed
CN-109566374-B High-yield pea seedling and planting method thereof 刘斌 2021-04-06 CN disclosed
CN-109566351-A A kind of culture substrate improving bud ratio 李靖 2019-04-05 CN disclosed
CN-109566374-A A kind of high yield pea seedlings and its implantation methods 李靖 2019-04-05 CN disclosed
EP-2513113-B1 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITORS IDENIX PHARMACEUTICALS LLC (US) 2018-08-01 EP disclosed
EP-2491041-B1 BIVALENT DIAZO BICYCLIC SMAC MIMETICS AND THE USES THEREOF UNIV MICHIGAN REGENTS (US) 2017-08-09 EP disclosed
US-8445473-B2 Heteroaryl-substituted bicyclic Smac mimetics and the uses thereof THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2013-05-21 US disclosed
EP-0251760-A2 Rubber composition Bridgestone Corporation (JP) 1988-01-07 EP disclosed