Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.52 |
| ▸ | BACE1 | P56817 | 11/20 | 0.52 |
| ▸ | BCHE | P06276 | 8/20 | 0.52 |
| ▸ | FABP6 | P51161 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640261 | 0.81 | ACHE (0.55) | ACHEBACE1BCHEFABP6CARM1 | |
| SCHEMBL9233879 | 0.75 | ACHE (0.51) | ACHEBACE1BCHEFABP6CARM1 | |
| SCHEMBL11371929 | 0.75 | ACHE (0.60) | ACHEBACE1BCHEFABP6CARM1 | |
| SCHEMBL8081164 | 0.74 | ACHE (0.68) | ACHEBACE1BCHEFABP6CARM1 | |
| SCHEMBL13848430 | 0.73 | DRD4 (0.57) | ACHEBACE1BCHEFABP6CARM1 | |
| SCHEMBL3757285 | 0.72 | IDO1 (0.44) | ACHEBACE1BCHECARM1PRMT6 | |
| SCHEMBL20492779 | 0.71 | CARM1 (0.68) | ACHEBACE1BCHECARM1PRMT6 | |
| SCHEMBL663239 | 0.71 | GRIN2B (0.74) | ACHEBACE1BCHECARM1PRMT6 | |
| SCHEMBL29238649 | 0.71 | DRD4 (0.61) | ACHEBACE1BCHEFABP6CARM1 | |
| SCHEMBL16538645 | 0.71 | HRH3 (0.63) | ACHEBACE1BCHECARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |