Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16132580 | 0.77 | — | — | |
| SCHEMBL29220483 | 0.75 | ALDH1A1 (0.33) | ALDH1A1TDP1TP53TSHRSMN1; SMN2 | |
| SCHEMBL28033720 | 0.73 | — | — | |
| SCHEMBL10770944 | 0.71 | ALDH1A1 (0.38) | ALDH1A1TDP1TP53TSHRSMN1; SMN2 | |
| SCHEMBL20022659 | 0.69 | — | — | |
| SCHEMBL27535589 | 0.69 | — | — | |
| SCHEMBL6436306 | 0.68 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL4990894 | 0.68 | TSHR (0.46) | ALDH1A1TDP1TP53TSHRSMN1; SMN2 | |
| Phosphoric Acid SCHEMBL5790727 | 0.65 | ALDH1A1 (0.35) | ALDH1A1TDP1TP53TSHRSMN1; SMN2 | |
| SCHEMBL1700640 | 0.65 | TSHR (0.44) | ALDH1A1TDP1TP53TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264038-A1 | Cytostatics containing glycidyl groups | Henkel Kommanditgesellschaft auf Aktien (DE) | 1988-04-20 | — | — | EP | disclosed |